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Ankylosing Spondylitis

Ankylosing spondylitis is a chronic inflammatory condition that primarily affects the spine and sacroiliac joints. It can cause persistent back pain, stiffness, and reduced flexibility, particularly in younger …

4 MIN READ· PHYSICIAN-REVIEWED· UPDATED 2026

Ankylosing spondylitis is a chronic inflammatory condition that primarily affects the spine and sacroiliac joints. It can cause persistent back pain, stiffness, and reduced flexibility, particularly in younger adults. Over time, ongoing inflammation may affect posture and spinal mobility if not appropriately managed.

Symptoms often develop gradually and may be mistaken for mechanical back pain. Early recognition and specialized care can play an important role in managing inflammation and preserving function.

What Is Ankylosing Spondylitis?

Ankylosing spondylitis is an autoimmune inflammatory arthritis that mainly involves the axial skeleton, including the spine and pelvis. Inflammation occurs at the sites where ligaments and tendons attach to bone, leading to pain and stiffness.

Unlike degenerative spinal conditions, ankylosing spondylitis is driven by immune-mediated inflammation and often presents with symptoms that improve with activity rather than rest.

Common Symptoms

Common symptoms may include:

  • Chronic lower back pain lasting several months
  • Morning stiffness that improves with movement
  • Reduced spinal flexibility
  • Pain in the hips or buttocks
  • Fatigue
  • Discomfort that may wake patients during the night

Symptoms may progress slowly and vary in intensity over time.

What Causes Ankylosing Spondylitis?

The precise cause is not fully understood, but contributing factors may include:

  • Genetic predisposition
  • Immune system activation leading to chronic inflammation
  • Environmental triggers

Certain genetic markers are commonly associated with this condition, though not everyone with these markers develops disease.

How Is Ankylosing Spondylitis Diagnosed?

Diagnosis often requires a detailed evaluation, including:

  • Review of symptom patterns and medical history
  • Physical examination focusing on spinal mobility
  • Laboratory tests to assess inflammatory markers
  • Imaging studies to evaluate the spine and sacroiliac joints

Early diagnosis can help guide management and reduce long-term complications.

Treatment Options for Ankylosing Spondylitis

Management is tailored to each patient and may include:

  • Anti-inflammatory therapies to control pain and stiffness
  • Medications aimed at reducing immune-mediated inflammation
  • Advanced therapies for persistent disease activity
  • Infusion-based treatments when clinically indicated
  • Exercise and physical therapy to maintain posture and flexibility

Long-term management focuses on controlling inflammation and preserving mobility.

When to See a Rheumatologist

A rheumatology evaluation may be appropriate if you experience:

  • Chronic back pain that improves with movement
  • Prolonged morning stiffness
  • Back pain beginning at a younger age
  • Symptoms that persist despite conservative measures

Specialized assessment may help clarify the cause of symptoms.

Our Approach to Treating Ankylosing Spondylitis

Our approach emphasizes early identification, personalized treatment planning, and ongoing monitoring. We work with patients to manage inflammation, support spinal health, and adapt care strategies as needed over time.

For those who may benefit from advanced or infusion-based therapies, we provide coordinated care in a supportive setting focused on long-term disease control.

Schedule a Consultation

If persistent back pain or stiffness is affecting your quality of life, scheduling a consultation may help determine whether ankylosing spondylitis or another inflammatory condition is contributing to your symptoms.

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