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Inflammatory & Immune-Mediated Conditions

Sarcoidosis

Sarcoidosis is an inflammatory condition characterized by the formation of granulomas, or clusters of immune cells, in various organs. It most commonly affects the lungs and lymph nodes but can also involve the…

4 MIN READ· PHYSICIAN-REVIEWED· UPDATED 2026

Sarcoidosis is an inflammatory condition characterized by the formation of granulomas, or clusters of immune cells, in various organs. It most commonly affects the lungs and lymph nodes but can also involve the joints, skin, eyes, and other tissues. Symptoms can range from mild to more significant depending on organ involvement.

Because sarcoidosis can affect multiple systems, comprehensive evaluation and coordinated care are important.

What Is Sarcoidosis?

Sarcoidosis is an immune-mediated inflammatory disease in which granulomas form in affected tissues. These granulomas can interfere with normal organ function depending on their location and extent.

The condition is systemic and inflammatory rather than degenerative.

Common Symptoms

Symptoms of sarcoidosis may include:

  • Fatigue
  • Joint pain or swelling
  • Shortness of breath or cough
  • Skin changes or rashes
  • Eye irritation or visual symptoms
  • Enlarged lymph nodes

Symptoms vary widely between individuals.

What Causes Sarcoidosis?

The exact cause is not fully understood, but contributing factors may include:

  • Immune system dysregulation
  • Genetic susceptibility
  • Environmental triggers

Sarcoidosis is not contagious.

How Is Sarcoidosis Diagnosed?

Diagnosis involves a comprehensive evaluation that may include:

  • Review of symptoms and medical history
  • Physical examination
  • Imaging studies to assess organ involvement
  • Laboratory testing to evaluate inflammation
  • Tissue biopsy in select cases

Accurate diagnosis guides appropriate management.

Treatment Options for Sarcoidosis

Treatment depends on disease severity and organ involvement. Options may include:

  • Observation for mild disease
  • Anti-inflammatory or immune-modulating therapies
  • Advanced therapies for persistent or systemic involvement
  • Infusion-based treatments when clinically appropriate
  • Ongoing monitoring of organ function

Management is individualized.

When to See a Rheumatologist

A rheumatology evaluation may be appropriate if you experience:

  • Joint pain with systemic symptoms
  • Persistent inflammation affecting multiple organs
  • Unclear diagnosis following initial evaluation

Specialized care helps guide treatment.

Our Approach to Treating Sarcoidosis

Our approach emphasizes comprehensive evaluation, individualized treatment planning, and coordinated care across specialties. We monitor disease activity and adjust therapy to support long-term health.

Advanced therapies are considered when appropriate.

Schedule a Consultation

If symptoms related to sarcoidosis are affecting your joints or overall health, scheduling a consultation can help clarify diagnosis and guide appropriate management.

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